♥ Solid Phase Extraction (SPE) is an extraction method that uses a solid phase and a liquid phase to isolate one, or one type, of analyte from a solution. It is usually used to clean up a sample before using a chromatographic or other analytical method to quantitate the amount of analyte(s) in the sample.

The general solid phase extraction procedure is to load a solution onto the stationary phase, wash away undesired components, and then wash off the desired analytes with another solvent into a collection tube. Solid phase extractions performed by instruments use the same type of stationary phases as are used in liquid chromatography columns. The stationary phase is contained in a glass or plastic column above a frit or glass wool. The column might have a frit on top of the stationary phase and might also have a stopcock to control the flow of solvent through the column. Commercial solid phase extraction cartridges have 1 to 60 mL capacities and are discarded after use. A vacuum manifold or positive pressure pump which increases the solvent flow rate through the cartridge is sometimes used. A collection tube is placed beneath the SPE cartridge to collect the liquid that passes through the column.

SPE is used to for many sample matrix types such as: water, beverages, serum, urine, milk, pharmaceuticals and food products. Some sample matrices are complex and have multiple interferences that make it difficult to analyze the compound of interest. You can use solid phase extraction to remove these interferences and to improve the quantification of the target compounds. SPE can also clean up the sample matrix, keeping your analytical instruments, such as mass spectrometers, free of reduced responses. SPE is also used as a fractionation tool that allows you to separate a large range of compounds from one sample, such as aliphatic and aromatic hydrocarbons from an extractable petroleum hydrocarbon sample. It allows for one sample to be analyzed for two things. SPE is effective for concentrating trace levels of compounds of interest onto the SPE cartridge by passing large volumes of sample matrix across the cartridge and then eluting the compounds of interest off of the SPE cartridge.

turbo trace


Dimensions: 15” W x 18” D x 35” H

Weight: 130 lbs.

Gas Requirements: Nitrogen – 20 PSI minimum

Vacuum Requirements: 25” Hg minimum

Pump: Piston Displacement

Flow rate: 0.2 to 15 mL/minute

Electrical Input: 110/220 Volts, 50/60 HZ

Controller: Integrated Touch Screen Control

SuperVap™ Concentration System

Dimensions: 7” W x 13” D x 12” H

Weight: 20 lbs.

Gas Requirements: Nitrogen – 20 PSI minimum

Electrical Input: 110/220 Volts, 50/60 HZ

Controller: Integrated Touch Screen Control

Bath: Dry